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Glutamate is the most abundant signaling molecule in the brain. The aim of the project is to develop molecules that can modulate glutamate signalling mediated by the so-called kainate receptors, but only in specific areas of the brain where the regulatory protein NETO is present.  Such molecules can give us a better understanding of communication in the brain, but also lead to better treatment of neurologic disorders where glutamate is involved, i.e. epilepsy, Alzheimer's and more.