Â鶹Éç

Current stem cell-based replacement therapies for Parkinson’s disease yield only a small percentage of cells that develop into the desired dopamine neurons. Increasing the purity of these dopamine neurons is vital for restoring movement in patients and eliminating potentially harmful unwanted cells. In this project, we will employ a gene-editing approach to engineer stem cells that are lineage-restricted and prevented from generating incorrect cell types. This approach aims to develop a more effective and safer treatment option for millions of patients worldwide.