Meet Jariwala
Decoding neural circuits in psychiatry: A focus on the molecular basis of behavioral disorders.
Neuropsychiatric disorders, impacting 1 in 8 globally, have limited treatment options and cause societal integration challenges due to insufficient understanding of brain circuits and molecular mechanisms. I will implement a novel paradigm for labelling psychiatric behaviour-associated circuits in the whole brain and determine how brain cell-types and circuits are modulated by impaired behaviour associated with key neuropsychiatric manifestations. Further, I aim to identify risk genes and molecular mechanisms of perturbed circuits at single cell resolution using transcriptomics. Combining both challenging techniques will help me to correlate behavioral symptoms at circuit-level and at transcriptomic-level in a robust genetic model of psychiatry.
